Anti-Bacterial effect, fluoride release, and compressive strength of a glass ionomer containing silver and titanium nanoparticles

Anti-Bacterial effect, fluoride release, and compressive strength of a glass ionomer containing silver and titanium nanoparticles

Blog Article

Background: Many attempts have been made to enhance the anti-cariogenic properties of LIPOSOMAL VITAMIN C 1000 the conventional glass ionomer through incorporation of variable materials.However, most importantly, the incorporation of such materials should not jeopardise the physical or mechanical properties of the final restoration.Aims: To investigate the effect of adding silver nanoparticles (Ag-NPs) and titanium dioxide nanoparticles (TiO2-NPs) to conventional glass ionomer cement (GIC) on its anti-bacterial effect against Streptococcus mutans (S.mutans), fluoride ion release, and compressive strength (CS).

Settings and Design: This study was an in vitro investigation where 30-disc specimens were prepared in each of the three studied groups.Materials and Methods: The specimens were categorized into the control group (Group C), in which conventional GIC was used, and Group Ag and Group Ti, in which 5 wt% of Ag-NP and TiO2-NP were added, respectively, to GIC powder.In each group, the anti-bacterial effect against S.mutans, fluoride ion release at 24 hours and 14 and 28 days, and CS were assessed.

Data were analysed using one-way analysis of variance, followed by Tukey honest significant difference post-hoc test.Results: Both Ag and Ti groups showed a significantly higher 5-Piece Sectional with Storage Consoles anti-bacterial effect than the control group.Ag-NP increased fluoride ion release, whereas TiO2-NP decreased fluoride release; however, cumulative ion release of both experimental groups did not differ significantly compared to the control group.Adding Ag-NP and TiO2-NP increased CS, yet only the Ti group showed the highest CS mean value that was statistically significant compared to other groups.

Conclusions: Adding 5 wt% TiO2-NP or Ag-NP to conventional GIC significantly increased its anti-bacterial effect and its CS without affecting fluoride release.